The Cost Effectiveness of Lubiprostone in Chronic Idiopathic Constipation
نویسندگان
چکیده
منابع مشابه
Lubiprostone: a novel treatment for chronic constipation
Chronic constipation is highly prevalent, reduces patients' quality of life, and imposes a significant health care burden on society. Lifestyle modifications and over-the-counter agents improve symptoms of constipation in some patients, however many patients have persistent symptoms and require the use of prescription medications. Three prescription medications are currently Food and Drug Admin...
متن کاملA critical appraisal of lubiprostone in the treatment of chronic constipation in the elderly
Chronic constipation is a common disorder in the general population, with higher prevalence in the elderly, and is associated with worse quality of life and with greater health care utilization. Lubiprostone is an intestinal type-2 chloride channel activator that increases intestinal fluid secretion, small intestinal transit, and stool passage. Lubiprostone is currently approved by the US Food ...
متن کاملSevere chronic constipation of young women: 'idiopathic slow transit constipation'.
A series of 64 women complaining of severe constipation is described, in each of whom delayed elimination of markers from the colon was demonstrated but a barium enema was normal. All completed a detailed questionnaire and the responses are compared with those obtained in an age-matched series of healthy women with no bowel complaint. In each group 40 women also recorded in a manner suitable fo...
متن کاملCost-effectiveness of prucalopride in the treatment of chronic constipation in the Netherlands
OBJECTIVE To assess the cost-effectiveness of prucalopride vs. continued laxative treatment for chronic constipation in patients in the Netherlands in whom laxatives have failed to provide adequate relief. METHODS A Markov model was developed to estimate the cost-effectiveness of prucalopride in patients with chronic constipation receiving standard laxative treatment from the perspective of D...
متن کاملLubiprostone for the treatment of functional constipation in children.
OBJECTIVES Pediatric functional constipation is common; effective, easily administered treatment options are limited. Lubiprostone is an oral chloride channel protein-2 activator that stimulates gastrointestinal fluid secretion, softens stools, and facilitates bowel movements (BMs). We evaluated the safety and effectiveness of lubiprostone in children and adolescents with functional constipatio...
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ژورنال
عنوان ژورنال: PharmacoEconomics - Open
سال: 2018
ISSN: 2509-4262,2509-4254
DOI: 10.1007/s41669-017-0065-9